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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ADRB1
All Species:
17.88
Human Site:
S423
Identified Species:
39.33
UniProt:
P08588
Number Species:
10
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P08588
NP_000675.1
477
51323
S423
A
R
P
G
P
P
P
S
P
G
A
A
S
D
D
Chimpanzee
Pan troglodytes
XP_521608
476
51237
S422
A
R
P
G
P
P
P
S
P
G
A
A
S
D
D
Rhesus Macaque
Macaca mulatta
P47899
480
51591
S426
A
R
P
G
P
P
P
S
P
G
A
A
S
D
D
Dog
Lupus familis
Cat
Felis silvestris
Mouse
Mus musculus
P34971
466
50461
S412
A
R
A
G
P
P
P
S
P
G
A
P
S
D
D
Rat
Rattus norvegicus
P18090
466
50453
S412
A
R
A
G
P
P
P
S
P
G
A
P
S
D
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513543
477
52086
L424
R
H
R
L
L
L
L
L
L
G
A
G
P
E
G
Chicken
Gallus gallus
XP_428541
514
55555
V462
R
P
G
E
D
S
E
V
L
G
R
S
R
R
E
Frog
Xenopus laevis
O42574
385
43291
R337
D
F
R
K
A
F
K
R
L
L
C
C
P
K
K
Zebra Danio
Brachydanio rerio
NP_001122161
390
43773
S342
D
R
R
L
H
V
S
S
C
D
L
S
R
C
T
Tiger Blowfish
Takifugu rubipres
P53452
459
51062
E402
H
S
I
L
C
Q
E
E
E
L
Q
K
K
D
G
Fruit Fly
Dros. melanogaster
Q4LBB9
536
60360
W488
L
C
L
F
C
N
W
W
K
D
R
H
L
P
L
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.5
97.5
N.A.
N.A.
90.9
90.7
N.A.
72.7
51.3
53.8
52.4
26.4
31.8
N.A.
N.A.
N.A.
Protein Similarity:
100
98.7
97.5
N.A.
N.A.
91.8
91.8
N.A.
78.8
63.8
64.7
64.7
43.1
45.7
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
13.3
6.6
0
13.3
6.6
0
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
N.A.
N.A.
86.6
86.6
N.A.
20
20
0
20
6.6
0
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
46
0
19
0
10
0
0
0
0
0
55
28
0
0
0
% A
% Cys:
0
10
0
0
19
0
0
0
10
0
10
10
0
10
0
% C
% Asp:
19
0
0
0
10
0
0
0
0
19
0
0
0
55
46
% D
% Glu:
0
0
0
10
0
0
19
10
10
0
0
0
0
10
10
% E
% Phe:
0
10
0
10
0
10
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
46
0
0
0
0
0
64
0
10
0
0
19
% G
% His:
10
10
0
0
10
0
0
0
0
0
0
10
0
0
0
% H
% Ile:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
10
0
0
10
0
10
0
0
10
10
10
10
% K
% Leu:
10
0
10
28
10
10
10
10
28
19
10
0
10
0
10
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
10
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
10
28
0
46
46
46
0
46
0
0
19
19
10
0
% P
% Gln:
0
0
0
0
0
10
0
0
0
0
10
0
0
0
0
% Q
% Arg:
19
55
28
0
0
0
0
10
0
0
19
0
19
10
0
% R
% Ser:
0
10
0
0
0
10
10
55
0
0
0
19
46
0
0
% S
% Thr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
10
% T
% Val:
0
0
0
0
0
10
0
10
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
10
10
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _